Cannatrek T22 Mackay Flower 10g
Cannatrek T22 Mackay Flower 10g
This is a Prescription Only Medication. Please email us the prescription and the doctors permit to firstname.lastname@example.org.
Cannatrek T22® MacKay™️ Flower is a Indica:Sativa balanced hybrid, dried medicinal cannabis flower. Each gram of dried flower contains 22% (w/w) THC (Delta-9-tetrahydrocannabinol).
Cannatrek T22® MackayTM Flower is psychoactive and may lead to temporary cognitive impairment. Patients are advised not to drive or operate heavy/ complex machinery whilst taking THC containing medication.
Cannatrek dried flower medications are designed for inhalation and are dosed via a vaporiser. Many patients prefer dried cannabis flower due to its rapid onset of action when compared to edible oils. Dried cannabis flower may be administered on a metered dosage schedule or PRN. While patients may experience medicinal benefits after their first dose, over time, patients can begin to develop a tolerance to THC. Patients may need to increase their dose in order to achieve the same desired eff ect (1).
What are the effects of inhaling dried cannabis compared to ingesting cannabis oil?
Inhaling dried cannabis flower provides a faster onset of action
but shorter lasting effects when compared to ingesting cannabis
oil (see graphic). When cannabis is inhaled, the effects are almost immediate with an onset of action in 5 to 10 minutes and duration
of 2 to 4 hours. When ingesting cannabis, onset of action can take
60 to 180 minutes and may last for up to 6 to 8 hours (3).
This variance is due to several factors including potency and quantity
of cannabis consumed, tolerance of the user and mechanism of delivery. In addition, there are many patient variables that can influence the effects of ingested cannabis oil such as the time of day, empty or full stomach metabolism and tolerance.
To accurately gauge the effects of cannabis, it is recommended to take the same dose under the same conditions every day. It is important to know that dried cannabis and cannabis oils can be used separately or together in achieving a desired outcome.
Why are the effects of ingesting cannabis oil different compared to inhalation?
When cannabis is inhaled, cannabinoids are absorbed from the lungs into the bloodstream within minutes. In the bloodstream, the cannabinoids are transported to the brain. Maximum concentrations of cannabinoids in the brain are achieved in less than 15 minutes, correlating with peak psychological and physiological effects. Effect may vary between individuals based on factors including heating of the cannabis, number of inhalations, wait time between inhalations, the inhalation period and lung capacity.
When cannabis is consumed orally, absorption of cannabinoids into the bloodstream via the digestive system is slower and more unpredictable. Onset of action commonly takes 60 to 180 minutes with maximum effect experienced at 2-4 hours. Once in the bloodstream, isoenzymes CYP2C9 and CYP3A4 of the cytochrome P450 system in the liver convert THC to the biologically active metabolite 11-hydroxy-THC (11-OH-THC). 11-hydroxy-THC is a psychoactive metabolite of THC with sedative effects. This metabolite appears at much lower levels when cannabis is inhaled. Finally, THC and CBD concentrations are higher in the liver after oral administration.
What is the recommended method for inhaling dried cannabis flower?
Vaporisation is the recommended method for inhaling dried medical cannabis flower.
Recommended = Vaporisation
A vaporiser is a device that heats dried medical cannabis without causing combustion. Vaporisation produces a vapour rich in cannabinoids that can be inhaled directly. There are several different models of vaporisers that patients can explore to see which one works best for them. Some points on vaporisation:
• Much more efficient than smoking.
• Does not produce undesirable compounds that can cause lung irritation.
• A typical vaporizer bowl holds between 0.1 to 0.25 gram.
Not Recommended = Combustion
Combustion refers to several different methods including a pipe or rolled cannabis cigarette (‘joint’). Combustion is not recommended as smoking can contribute to COPD (chronic obstructive pulmonary disease) and produces undesirable compounds that can be irritating to the lungs. Some things to consider related to combustion:
• Up to 30% of the active ingredients are lost in side stream
smoke and combustion.
• A typical cannabis joint contains between 0.5 to 1 gram.